منابع مشابه
The Halophile Protein Database
Halophilic archaea/bacteria adapt to different salt concentration, namely extreme, moderate and low. These type of adaptations may occur as a result of modification of protein structure and other changes in different cell organelles. Thus proteins may play an important role in the adaptation of halophilic archaea/bacteria to saline conditions. The Halophile protein database (HProtDB) is a syste...
متن کاملPrebiotic protein design supports a halophile origin of foldable proteins
There are significant challenges in forming testable hypotheses regarding abiogenesis (i.e., the origin of life); for example, the original environment on the early Earth during the process of abiogenesis is a matter of debate [although it was significantly different from the current environment (Oparin, 1952; Hazen et al., 2008)]. Furthermore, the process of abiogenesis occurred over a time sc...
متن کاملRaman spectroscopy in halophile research
Raman spectroscopy plays a major role in robust detection of biomolecules and mineral signatures in halophile research. An overview of Raman spectroscopic investigations in halophile research of the last decade is given here to show advantages of the approach, progress made as well as limits of the technique. Raman spectroscopy is an excellent tool to monitor and identify microbial pigments and...
متن کاملAnalysis of protein solvent interactions in glucose dehydrogenase from the extreme halophile Haloferax mediterranei.
The structure of glucose dehydrogenase from the extreme halophile Haloferax mediterranei has been solved at 1.6-A resolution under crystallization conditions which closely mimic the "in vivo" intracellular environment. The decoration of the enzyme's surface with acidic residues is only partially neutralized by bound potassium counterions, which also appear to play a role in substrate binding. T...
متن کاملPfam: the protein families database
Pfam, available via servers in the UK (http://pfam.sanger.ac.uk/) and the USA (http://pfam.janelia.org/), is a widely used database of protein families, containing 14 831 manually curated entries in the current release, version 27.0. Since the last update article 2 years ago, we have generated 1182 new families and maintained sequence coverage of the UniProt Knowledgebase (UniProtKB) at nearly ...
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ژورنال
عنوان ژورنال: Database
سال: 2014
ISSN: 1758-0463
DOI: 10.1093/database/bau114